AcroPak™ filters with Fluorodyne™ II membrane, a Pall Life Sciences product, are compatible with aqueous and many organic solvents
Materials of construction
Filter Media: Fluorodyne II membrane (hydrophilic PVDF)
Housing, Vent Plug: Polypropylene
Sealing Technology: Thermal bonding
Filling Bell: Polycarbonate
Pore Size
0.1 and 0.2 μm
Effective Filtration Area
20 and 200 cm2
Dimensions (Nominal)
AcroPak 20 Filters
Housing Length: 8.3 cm (3.3 in.)
Housing Diameter: 6.7 cm (2.7 in.)
AcroPak 200 Capsule
Overall Length: 10.5 cm (4.1 in.)
Housing Diameter Without Vent: 5.3 cm (2.1 in.)
Housing Diameter With Vent: 6.7 cm (2.6 in.)
AcroPak 20 filters are designed to add convenience to small- and medium-volume filtrations
AcroPak 200 Fluorodyne II capsules provide fast processing of clean batches
Double layer sterilizing membrane enhances reliability
Upstream air vent prevents vapor lock
Manufactured without the use of adhesives to minimize extractables
Pre-sterilized by gamma irradiation
Inlet/Outlet Connections
6.4 - 12.7 mm (1/4 - 1/2 in.) diameter stepped hose barb with female luer slip interior and filling bell outlet
Maximum Operating Temperature and Pressure
60°C (140°F) at 1.0 bar (100 kPa, 15 psi)
4.1 bar (410 kPa, 60 psi) at 21 - 24°C (70 - 75°F)
Recommended Integrity Test Minimum Bubble Point – Water
0.2 μm Fluorodyne II membrane: 3.2 bar (320 kPa, 46 psi)
60% IPA/40% H2O (v:v)
0.1 μm Fluorodyne II membrane: 1.8 bar (180 kPa, 26 psi)
Typical Water Flow Rate mL/min at 0.1 bar (10 kPa) [mL/min/psi]
AcroPak 20 Filters
0.1 μm Fluorodyne II Membrane: 13 (9)
0.2 μm Fluorodyne II Membrane: 26 (18)
AcroPak 200 Capsule
0.2 μm Fluorodyne II Membrane: 240 (170)
Typical Hold-Up Volume (with 10 psi air purge)
AcroPak 20 Filters < 2.5 mL
AcroPak 200 Capsule < 6 mL
Bacterial Retention
Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Sterilized by gamma irradiation and individually packaged
AcroPak 20 filters can withstand one autoclave cycle at 131°C (268°F) for 30 min
Applications
Sterile filtration of media and buffers
Point-of-use filtration for lab water
Suitable for viscous, particulate solutions and serum containing media
Applicable for many fluids containing dilute proteins or preservatives
Scalable
Efficient processing volumes up to 20L. Fluorodyne II membrane is compatible with aqueous and many organic solvents. AcroPak 20 filters are designed to add convenience to small- and medium-volume filtrations.