Materials of Construction
Filter Media: Supor™ membrane [hydrophilic polyethersulfone (PES)]
Serum Acrodisc Prefilter Media: Binder-free borosilicate glass
Acrodisc Housing:
13 mm: Polypropylene
25 and 32 mm: Modified acrylic
37 mm: Polypropylene
Serum Acrodisc Housing: ABS
Pore Size
0.1, 0.2, 0.45, 0.8, 1.2, and 5 µm
Effective Filtration Area
13 mm: 1.0 cm2
25 mm: 2.8 cm2
32 mm: 5.8 cm2
37 mm: 7.5 cm2
Inlet/Outlet Connections
Female luer lock inlet, male slip luer outlet
Typical Hold-Up Volume
(with air purge)
13 mm: < 28 µL
25 mm: < 70 µL
32 and 37 mm: <100 µL
Maximum Operating Temperature
55°C (131°F)
Maximum Operating Pressure
5.2 bar (520 kPa, 75 psi)
Typical Water Flow Rate
mL/min at 3.1 bar (310 kPa, 45 psi)
0.1 μm, 25 mm: 35
0.1 μm, 32 mm: 100
0.2 μm, 13 mm: 22
0.2 μm, 25 mm: 175
0.2 μm, 32 mm: 490
0.45 μm, 13 mm: 35
0.45 μm, 25 mm: 300
0.45 μm, 32 mm: 700
0.8 μm, 13 mm: 150
0.8 μm, 25 mm: 700
0.8/0.2 μm, 25 mm: 145
0.8/0.2 μm, 32 mm: 440
1.2 μm, 32 mm: 1700
5 μm, 32 mm: 1750
GF/0.2 μm, 37 mm (Serum
Acrodisc Filter): 425
Endotoxin Level
13mm and 25mm: < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
32mm: < 0.4 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Sterilized by gamma irradiation and individually blister packaged. All bulk packages provided non-sterile including PN 4504, 4506, 4508, 4509, 4655, 4653, 4659, 4660, 4661, 4662, 4668, and 4692.
Applications
0.1 and 0.2 μm pore sizes provide sterilization of small volumes of buffers, culture media, and additives.
Acrodisc PF and Serum Acrodisc syringe filters are ideal for clarification/sterilization of viscous or particulate-laden solutions.
Use larger pore size filters for prefiltration and particulate removal.